Link: http://www.nlm.nih.gov/medlineplus/news/fullstory_90828.html
In this new study, Dr. C. Kent Kwoh, professor of medicine and epidemiology in the university's division of rheumatology and clinical immunology, had 201 people with mild to moderate knee pain randomly assigned to receive glucosamine or placebo. The study participants underwent MRI and X-ray screening at the start of the trial and 24 weeks later.
Kwoh's group found the same progression of cartilage damage in those who received glucosamine as in those who received placebo. Worsening bone lesions were also the same for both groups, and there was no difference in cartilage synthesis between the groups, the researchers noted.
"In this six-month study using state-of-the-art MR imaging, we were not able to demonstrate any benefit of glucosamine on the prevention of worsening joint damage in individuals with mild to moderate knee pain," Kwoh said in a prepared statement.


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